The PHGDH Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PHGDH. This antibody recognizes Human, Mouse, and Rat antigen. The PHGDH Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Function: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.
Subunit Structure: Homotetramer.
Similarity: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family